Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin

Sphingosine-1-phosphate (S1P) participates in inflammation; however, its role in leukocyte rolling is still unclear. Here we use intravital microscopy in inflamed mouse cremaster muscle venules and human endothelial cells to show that S1P contributes to P-selectin-dependent leukocyte rolling through...

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Detalles Bibliográficos
Autores principales: Nussbaum, Claudia, Bannenberg, Sarah, Keul, Petra, Gräler, Markus H., Gonçalves-de-Albuquerque, Cassiano F., Korhonen, Hanna, von Wnuck Lipinski, Karin, Heusch, Gerd, de Castro Faria Neto, Hugo C., Rohwedder, Ina, Göthert, Joachim R., Prasad, Vysakh Pushpa, Haufe, Günter, Lange-Sperandio, Baerbel, Offermanns, Stefan, Sperandio, Markus, Levkau, Bodo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396399/
https://www.ncbi.nlm.nih.gov/pubmed/25832730
http://dx.doi.org/10.1038/ncomms7416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396399/
https://www.ncbi.nlm.nih.gov/pubmed/25832730
http://dx.doi.org/10.1038/ncomms7416

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