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Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin
Sphingosine-1-phosphate (S1P) participates in inflammation; however, its role in leukocyte rolling is still unclear. Here we use intravital microscopy in inflamed mouse cremaster muscle venules and human endothelial cells to show that S1P contributes to P-selectin-dependent leukocyte rolling through...
Autores principales: | Nussbaum, Claudia, Bannenberg, Sarah, Keul, Petra, Gräler, Markus H., Gonçalves-de-Albuquerque, Cassiano F., Korhonen, Hanna, von Wnuck Lipinski, Karin, Heusch, Gerd, de Castro Faria Neto, Hugo C., Rohwedder, Ina, Göthert, Joachim R., Prasad, Vysakh Pushpa, Haufe, Günter, Lange-Sperandio, Baerbel, Offermanns, Stefan, Sperandio, Markus, Levkau, Bodo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396399/ https://www.ncbi.nlm.nih.gov/pubmed/25832730 http://dx.doi.org/10.1038/ncomms7416 |
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