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Local mechanisms for loud sound-enhanced aminoglycoside entry into outer hair cells

Loud sound exposure exacerbates aminoglycoside ototoxicity, increasing the risk of permanent hearing loss and degrading the quality of life in affected individuals. We previously reported that loud sound exposure induces temporary threshold shifts (TTS) and enhances uptake of aminoglycosides, like g...

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Detalles Bibliográficos
Autores principales: Li, Hongzhe, Kachelmeier, Allan, Furness, David N., Steyger, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396448/
https://www.ncbi.nlm.nih.gov/pubmed/25926770
http://dx.doi.org/10.3389/fncel.2015.00130