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Methylation of Promoter Regions of Genes of the Human Intrauterine Renin Angiotensin System and Their Expression

The intrauterine renin angiotensin system (RAS) is implicated in placentation and labour onset. Here we investigate whether promoter methylation of RAS genes changes with gestation or labour and if it affects gene expression. Early gestation amnion and placenta were studied, as were term amnion, dec...

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Detalles Bibliográficos
Autores principales: Sykes, Shane D., Mitchell, Carolyn, Pringle, Kirsty G., Wang, Yu, Zakar, Tamas, Lumbers, Eugenie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396557/
https://www.ncbi.nlm.nih.gov/pubmed/25918528
http://dx.doi.org/10.1155/2015/459818