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The potential of follicle-stimulating hormone peptide-modified triptolide-loaded nanoparticles to induce a mouse model of premature ovarian insufficiency

The use of triptolide (TP) is limited by its poor water solubility and severe toxicity. In this study, we developed an active drug delivery system (TP-loaded nanoparticles) that could help improve the water solubility of TP and decrease its toxicity. Then, we investigated whether TP-loaded nanoparti...

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Detalles Bibliográficos
Autores principales: Chen, Xiu-Ying, Chen, Wu-Lian, Ma, Min, Gu, Chao, Xiao, Xi-Rong, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396643/
https://www.ncbi.nlm.nih.gov/pubmed/25897221
http://dx.doi.org/10.2147/IJN.S72593