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Study of PTEN subcellular localization

The tumor suppressor PTEN is a key regulator of a plethora of cellular processes that are crucial in cancer development. Through its lipid phosphatase activity PTEN suppresses the PI3K/AKT pathway to govern cell proliferation, growth, migration, energy metabolism and death. The repertoire of roles f...

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Detalles Bibliográficos
Autores principales: Bononi, Angela, Pinton, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396696/
https://www.ncbi.nlm.nih.gov/pubmed/25312582
http://dx.doi.org/10.1016/j.ymeth.2014.10.002