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Study of PTEN subcellular localization
The tumor suppressor PTEN is a key regulator of a plethora of cellular processes that are crucial in cancer development. Through its lipid phosphatase activity PTEN suppresses the PI3K/AKT pathway to govern cell proliferation, growth, migration, energy metabolism and death. The repertoire of roles f...
Autores principales: | Bononi, Angela, Pinton, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396696/ https://www.ncbi.nlm.nih.gov/pubmed/25312582 http://dx.doi.org/10.1016/j.ymeth.2014.10.002 |
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