O-Glycosylation in Cell Wall Proteins in Scedosporium prolificans Is Critical for Phagocytosis and Inflammatory Cytokines Production by Macrophages

In this study, we analyze the importance of O-linked oligosaccharides present in peptidorhamnomannan (PRM) from the cell wall of the fungus Scedosporium prolificans for recognition and phagocytosis of conidia by macrophages. Adding PRM led to a dose-dependent inhibition of conidia phagocytosis, wher...

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Detalles Bibliográficos
Autores principales: Xisto, Mariana I. D. S., Bittencourt, Vera C. B., Liporagi-Lopes, Livia Cristina, Haido, Rosa M. T., Mendonça, Morena S. A., Sassaki, Guilherme, Figueiredo, Rodrigo T., Romanos, Maria Teresa V., Barreto-Bergter, Eliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396840/
https://www.ncbi.nlm.nih.gov/pubmed/25875427
http://dx.doi.org/10.1371/journal.pone.0123189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396840/
https://www.ncbi.nlm.nih.gov/pubmed/25875427
http://dx.doi.org/10.1371/journal.pone.0123189

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