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Dipeptidyl Peptidase-4 Inhibitor Decreases Abdominal Aortic Aneurysm Formation through GLP-1-Dependent Monocytic Activity in Mice

Abdominal aortic aneurysm (AAA) is a life-threatening situation affecting almost 10% of elders. There has been no effective medication for AAA other than surgical intervention. Dipeptidyl peptidase-4 (DPP-4) inhibitors have been shown to have a protective effect on cardiovascular disease. Whether DP...

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Detalles Bibliográficos
Autores principales: Lu, Hsin Ying, Huang, Chun Yao, Shih, Chun Ming, Chang, Wei Hung, Tsai, Chein Sung, Lin, Feng Yen, Shih, Chun Che
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396852/
https://www.ncbi.nlm.nih.gov/pubmed/25876091
http://dx.doi.org/10.1371/journal.pone.0121077