Targeted Knockdown of RNA-Binding Protein TIAR for Promoting Self-Renewal and Attenuating Differentiation of Mouse Embryonic Stem Cells

RNA-binding protein TIAR has been suggested to mediate the translational silencing of ARE-containing mRNAs. To analyze the functions of TIAR, we established RNAi and genetic rescue assays. We evaluated the expression of neuroectoderm markers Pax6 and nestin, mesoderm markers brachyury and Flk1, and...

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Detalles Bibliográficos
Autores principales: Geng, Zhe, Li, Ping, Tan, Li, Song, Houyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396887/
https://www.ncbi.nlm.nih.gov/pubmed/25918534
http://dx.doi.org/10.1155/2015/657325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396887/
https://www.ncbi.nlm.nih.gov/pubmed/25918534
http://dx.doi.org/10.1155/2015/657325

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