MT-4 Suppresses Resistant Ovarian Cancer Growth through Targeting Tubulin and HSP27

OBJECTIVE: In this study, the anticancer mechanisms of MT-4 were examined in A2780 and multidrug-resistant NCI-ADR/res human ovarian cancer cell lines. METHODS: To evaluate the activity of MT-4, we performed in vitro cell viability and cell cycle assays and in vivo xenograft assays. Immunoblotting a...

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Detalles Bibliográficos
Autores principales: Pai, Hui Chen, Kumar, Sunil, Shen, Chien-Chang, Liou, Jing Ping, Pan, Shiow Lin, Teng, Che Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397017/
https://www.ncbi.nlm.nih.gov/pubmed/25874627
http://dx.doi.org/10.1371/journal.pone.0123819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397017/
https://www.ncbi.nlm.nih.gov/pubmed/25874627
http://dx.doi.org/10.1371/journal.pone.0123819

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