Attenuation of Progressive Hearing Loss in DBA/2J Mice by Reagents that Affect Epigenetic Modifications Is Associated with Up-Regulation of the Zinc Importer Zip4

Various factors that are important for proper hearing have been identified, including serum levels of zinc. Here we investigated whether epigenetic regulatory pathways, which can be modified by environmental factors, could modulate hearing. RT-PCR detected expression of genes encoding DNA methyltran...

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Detalles Bibliográficos
Autores principales: Mutai, Hideki, Miya, Fuyuki, Fujii, Masato, Tsunoda, Tatsuhiko, Matsunaga, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397065/
https://www.ncbi.nlm.nih.gov/pubmed/25875282
http://dx.doi.org/10.1371/journal.pone.0124301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397065/
https://www.ncbi.nlm.nih.gov/pubmed/25875282
http://dx.doi.org/10.1371/journal.pone.0124301

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