Cargando…

Attenuation of Progressive Hearing Loss in DBA/2J Mice by Reagents that Affect Epigenetic Modifications Is Associated with Up-Regulation of the Zinc Importer Zip4

Various factors that are important for proper hearing have been identified, including serum levels of zinc. Here we investigated whether epigenetic regulatory pathways, which can be modified by environmental factors, could modulate hearing. RT-PCR detected expression of genes encoding DNA methyltran...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mutai, Hideki, Miya, Fuyuki, Fujii, Masato, Tsunoda, Tatsuhiko, Matsunaga, Tatsuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397065/ https://www.ncbi.nlm.nih.gov/pubmed/25875282 http://dx.doi.org/10.1371/journal.pone.0124301

Ejemplares similares

Gene expression profiling of DBA/2J mice cochleae treated with l-methionine and valproic acid
por: Miya, Fuyuki, et al.
Publicado: (2015)

Gene expression dataset for whole cochlea of Macaca fascicularis
por: Mutai, Hideki, et al.
Publicado: (2018)

A case report of reversible generalized seizures in a patient with Waardenburg syndrome associated with a novel nonsense mutation in the penultimate exon of SOX10
por: Suzuki, Noriomi, et al.
Publicado: (2018)

Variants encoding a restricted carboxy-terminal domain of SLC12A2 cause hereditary hearing loss in humans
por: Mutai, Hideki, et al.
Publicado: (2020)

Mitochondrial mutations in maternally inherited hearing loss
por: Mutai, Hideki, et al.
Publicado: (2017)

In silico modeling of the pore region of a KCNQ4 missense mutant from a patient with hearing loss
por: Namba, Kazunori, et al.
Publicado: (2012)

IMSindel: An accurate intermediate-size indel detection tool incorporating de novo assembly and gapped global-local alignment with split read analysis
por: Shigemizu, Daichi, et al.
Publicado: (2018)

Publisher Correction: IMSindel: An accurate intermediate-size indel detection tool incorporating de novo assembly and gapped global-local alignment with split read analysis
por: Shigemizu, Daichi, et al.
Publicado: (2018)

Topologically associating domain underlies tissue specific expression of long intergenic non-coding RNAs
por: Hamba, Yu, et al.
Publicado: (2023)

A Case of Undiagnosed Sleep Disorder with Hearing Difficulty and Dizziness
por: Goto, Fumiyuki, et al.
Publicado: (2016)

Quantitative trait loci on chromosome 5 for susceptibility to frequency-specific effects on hearing in DBA/2J mice
por: SUZUKI, Sari, et al.
Publicado: (2015)

C57BL/6J, DBA/2J, and DBA/2J.Gpnmb(+) mice have different visual signal processing in the inner retina
por: Porciatti, Vittorio, et al.
Publicado: (2010)

Presphenoidal synchondrosis fusion in DBA/2J mice
por: Adams, Allysa, et al.
Publicado: (2012)

Prevalence of TECTA mutation in patients with mid-frequency sensorineural hearing loss
por: Yamamoto, Nobuko, et al.
Publicado: (2017)

The Contribution of Anterior Segment Abnormalities to Changes in Intraocular Pressure in the DBA/2J Mouse Model of Glaucoma: DBA/2J-Gpnmb(+)/SjJ Mice as Critical Controls
por: Rohowetz, Landon J., et al.
Publicado: (2022)

High-throughput sequencing of the DBA/2J mouse genome
por: Wang, Xusheng, et al.
Publicado: (2010)

Effect of Bilastine on Diabetic Nephropathy in DBA2/J Mice
por: Verta, Roberta, et al.
Publicado: (2019)

The ZIP6/ZIP10 heteromer is essential for the zinc-mediated trigger of mitosis
por: Nimmanon, Thirayost, et al.
Publicado: (2020)

Heterogeneous Immunolocalisation of Zinc Transporters ZIP6, ZIP10 and ZIP14 in Human Normo- and Asthenozoospermic Spermatozoa
por: Protic, Isidora, et al.
Publicado: (2022)

Whole exome analysis of patients in Japan with hearing loss reveals high heterogeneity among responsible and novel candidate genes
por: Mutai, Hideki, et al.
Publicado: (2022)

Correlation between genotype and phenotype with special attention to hearing in 14 Japanese cases of NF2-related schwannomatosis
por: Oishi, Naoki, et al.
Publicado: (2023)

Quantification of multicellular colonization in tumor metastasis using exome‐sequencing data
por: Nishino, Jo, et al.
Publicado: (2020)

Retinal Ganglion Cell Dendritic Atrophy in DBA/2J Glaucoma
por: Williams, Pete A., et al.
Publicado: (2013)

A Murine Hypertrophic Cardiomyopathy Model: The DBA/2J Strain
por: Zhao, Wenyuan, et al.
Publicado: (2015)

Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice
por: Anderson, Michael G, et al.
Publicado: (2001)

Phenotype of the Aging-Dependent Spontaneous Onset of Hearing Loss in DBA/2 Mice
por: Seo, Min-Soo, et al.
Publicado: (2021)

Differential Expression of Large-Conductance Ca(2+)-Activated K Channels in the Carotid Body between DBA/2J and A/J Strains of Mice
por: Otsubo, Toshiki, et al.
Publicado: (2011)

DBA Survivor
por: LaRock, Thomas
Publicado: (2010)

Pan-Domain Analysis of ZIP Zinc Transporters
por: Lehtovirta-Morley, Laura E., et al.
Publicado: (2017)

Systematic analysis of mitochondrial genes associated with hearing loss in the Japanese population: dHPLC reveals a new candidate mutation
por: Mutai, Hideki, et al.
Publicado: (2011)

Antitumorigenic Evaluation of Thalidomide Alone and in Combination with Cisplatin in DBA2/J Mice
por: Ruddy, Jean Marie B., et al.
Publicado: (2002)

Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice
por: Howell, Gareth R, et al.
Publicado: (2013)

Meox2 Haploinsufficiency Accelerates Axonal Degeneration in DBA/2J Glaucoma
por: Buchanan, Rebecca A., et al.
Publicado: (2019)

Neuroglobin Can Prevent or Reverse Glaucomatous Progression in DBA/2J Mice
por: Cwerman-Thibault, Hélène, et al.
Publicado: (2017)

Loss of Retinogeniculate Synaptic Function in the DBA/2J Mouse Model of Glaucoma
por: Smith, Jennie C., et al.
Publicado: (2022)

Early Cytoskeletal Protein Modifications Precede Overt Structural Degeneration in the DBA/2J Mouse Model of Glaucoma
por: Wilson, Gina N., et al.
Publicado: (2016)

Different Actions of Intracellular Zinc Transporters ZIP7 and ZIP13 Are Essential for Dermal Development
por: Lee, Mi-Gi, et al.
Publicado: (2019)

High prevalence of CDH23 mutations in patients with congenital high-frequency sporadic or recessively inherited hearing loss
por: Mizutari, Kunio, et al.
Publicado: (2015)

Diverse spectrum of rare deafness genes underlies early-childhood hearing loss in Japanese patients: a cross-sectional, multi-center next-generation sequencing study
por: Mutai, Hideki, et al.
Publicado: (2013)

DBA/2J Mice Are Susceptible to Diabetic Nephropathy and Diabetic Exacerbation of IOP Elevation
por: Soto, Ileana, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_14l29l1prbsljsnsr80noql4rn