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Actin Inhibition Increases Megakaryocyte Proplatelet Formation through an Apoptosis-Dependent Mechanism

BACKGROUND: Megakaryocytes assemble and release platelets through the extension of proplatelet processes, which are cytoplasmic extensions that extrude from the megakaryocyte and form platelets at their tips. Proplatelet formation and platelet release are complex processes that require a combination...

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Detalles Bibliográficos
Autores principales: Avanzi, Mauro P., Izak, Marina, Oluwadara, Oluwasijibomi E., Mitchell, William Beau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397066/
https://www.ncbi.nlm.nih.gov/pubmed/25875470
http://dx.doi.org/10.1371/journal.pone.0125057