Cargando…
Actin Inhibition Increases Megakaryocyte Proplatelet Formation through an Apoptosis-Dependent Mechanism
BACKGROUND: Megakaryocytes assemble and release platelets through the extension of proplatelet processes, which are cytoplasmic extensions that extrude from the megakaryocyte and form platelets at their tips. Proplatelet formation and platelet release are complex processes that require a combination...
Autores principales: | Avanzi, Mauro P., Izak, Marina, Oluwadara, Oluwasijibomi E., Mitchell, William Beau |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397066/ https://www.ncbi.nlm.nih.gov/pubmed/25875470 http://dx.doi.org/10.1371/journal.pone.0125057 |
Ejemplares similares
-
Interferon a-induced SAMHD1 regulates human cultured megakaryocyte apoptosis and proplatelet formation
por: Bhatlekar, Seema, et al.
Publicado: (2021) -
High Doses of Romiplostim Induce Proliferation and Reduce Proplatelet Formation by Human Megakaryocytes
por: Currao, Manuela, et al.
Publicado: (2013) -
Inherited thrombocytopenia: novel insights into megakaryocyte maturation, proplatelet formation and platelet lifespan
por: Johnson, Ben, et al.
Publicado: (2016) -
D-dencichine Regulates Thrombopoiesis by Promoting Megakaryocyte Adhesion, Migration and Proplatelet Formation
por: Ding, Shilan, et al.
Publicado: (2018) -
Anti-apoptotic BCL2L2 increases megakaryocyte proplatelet formation in cultures of human cord blood
por: Bhatlekar, Seema, et al.
Publicado: (2019)