Cargando…
A General Framework for Thermodynamically Consistent Parameterization and Efficient Sampling of Enzymatic Reactions
Kinetic models provide the means to understand and predict the dynamic behaviour of enzymes upon different perturbations. Despite their obvious advantages, classical parameterizations require large amounts of data to fit their parameters. Particularly, enzymes displaying complex reaction and regulat...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397067/ https://www.ncbi.nlm.nih.gov/pubmed/25874556 http://dx.doi.org/10.1371/journal.pcbi.1004195 |