Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice

Merkel cell carcinoma (MCC) is a rare and deadly neuroendocrine skin tumor frequently associated with clonal integration of a polyomavirus, MCPyV, and MCC tumor cells express putative polyomavirus oncoproteins small T antigen (sTAg) and truncated large T antigen (tLTAg). Here, we show robust transfo...

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Detalles Bibliográficos
Autores principales: Verhaegen, Monique E., Mangelberger, Doris, Harms, Paul W., Vozheiko, Tracy D., Weick, Jack W., Wilbert, Dawn M., Saunders, Thomas L., Ermilov, Alexandre N., Bichakjian, Christopher K., Johnson, Timothy M., Imperiale, Michael J., Dlugosz, Andrzej A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397111/
https://www.ncbi.nlm.nih.gov/pubmed/25313532
http://dx.doi.org/10.1038/jid.2014.446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397111/
https://www.ncbi.nlm.nih.gov/pubmed/25313532
http://dx.doi.org/10.1038/jid.2014.446

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