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Cystathionine β-Synthase Inhibition Is a Potential Therapeutic Approach to Treatment of Ischemic Injury

Hydrogen sulfide (H(2)S) has been reported to exacerbate stroke outcome in experimental models. Cystathionine β-synthase (CBS) has been implicated as the predominant H(2)S-producing enzyme in central nervous system. When SH-SY5Y cells were transfected to overexpress CBS, these cells were able to syn...

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Detalles Bibliográficos
Autores principales: Chan, Su Jing, Chai, Chou, Lim, Tze Wei, Yamamoto, Mie, Lo, Eng H, Lai, Mitchell Kim Peng, Wong, Peter Tsun Hon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397212/
https://www.ncbi.nlm.nih.gov/pubmed/25873304
http://dx.doi.org/10.1177/1759091415578711