Divergence in Endothelin-1- and Bradykinin-Activated Store-Operated Calcium Entry in Afferent Sensory Neurons

Endothelin-1 (ET-1) and bradykinin (BK) are endogenous peptides that signal through Gαq/11-protein coupled receptors (GPCRs) to produce nociceptor sensitization and pain. Both peptides activate phospholipase C to stimulate Ca(2+) accumulation, diacylglycerol production, and protein kinase C activati...

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Detalles Bibliográficos
Autores principales: Szteyn, Kalina, Gomez, Ruben, Berg, Kelly A, Jeske, Nathaniel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397213/
https://www.ncbi.nlm.nih.gov/pubmed/25873305
http://dx.doi.org/10.1177/1759091415578714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397213/
https://www.ncbi.nlm.nih.gov/pubmed/25873305
http://dx.doi.org/10.1177/1759091415578714

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