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Loss of Feedback Inhibition via D2 Autoreceptors Enhances Acquisition of Cocaine Taking and Reactivity to Drug-Paired Cues

A prominent aspect of drug addiction is the ability of drug-associated cues to elicit craving and facilitate relapse. Understanding the factors that regulate cue reactivity will be vital for improving treatment of addictive disorders. Low availability of dopamine (DA) D2 receptors (D2Rs) in the stri...

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Detalles Bibliográficos
Autores principales: Holroyd, Kathryn B, Adrover, Martin F, Fuino, Robert L, Bock, Roland, Kaplan, Alanna R, Gremel, Christina M, Rubinstein, Marcelo, Alvarez, Veronica A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397408/
https://www.ncbi.nlm.nih.gov/pubmed/25547712
http://dx.doi.org/10.1038/npp.2014.336