Cargando…
Antioxidant and Antimycotic Activities of Two Native Lavandula Species from Portugal
The antioxidant and antimycotic activities of the essential oils and extracts of two native Portuguese Lavandula species, L. stoechas subsp. luisieri and L. pedunculata, were evaluated by in vitro assays. The total phenolics and flavonoids content were also determined. The antioxidant potential was...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397469/ https://www.ncbi.nlm.nih.gov/pubmed/25922611 http://dx.doi.org/10.1155/2015/570521 |
_version_ | 1782366706946015232 |
---|---|
author | Baptista, Rafael Madureira, Ana Margarida Jorge, Rita Adão, Rita Duarte, Aida Duarte, Noélia Lopes, Maria Manuel Teixeira, Generosa |
author_facet | Baptista, Rafael Madureira, Ana Margarida Jorge, Rita Adão, Rita Duarte, Aida Duarte, Noélia Lopes, Maria Manuel Teixeira, Generosa |
author_sort | Baptista, Rafael |
collection | PubMed |
description | The antioxidant and antimycotic activities of the essential oils and extracts of two native Portuguese Lavandula species, L. stoechas subsp. luisieri and L. pedunculata, were evaluated by in vitro assays. The total phenolics and flavonoids content were also determined. The antioxidant potential was assessed through DPPH radical scavenging, inhibition of lipid peroxidation (ILP), and DNA protection assays. All samples displayed a high DPPH scavenging activity, some of them showing concentration dependence. The majority of the samples were also able to inhibit lipid peroxidation. A strong correlation was observed between the results of DPPH and ILP assays and the flavonoids content of the samples. In the DNA protection assay, all the extracts were able to preserve DNA integrity. The antimycotic activity was performed against twelve fungi belonging to Basidiomycota and Ascomycota Divisions. L. stoechas subsp. luisieri exhibited the broadest activity spectra. L. pedunculata extracts were active against five fungi. Cryptococcus neoformans was the most sensitive, being inhibited by all the extracts. Our results led to the conclusion that L. stoechas subsp. luisieri and L. pedunculata can be useful as new sources of natural antioxidants and antimycotic agents, providing a possible valorization of the existing biodiversity and resources of Portuguese flora. |
format | Online Article Text |
id | pubmed-4397469 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43974692015-04-28 Antioxidant and Antimycotic Activities of Two Native Lavandula Species from Portugal Baptista, Rafael Madureira, Ana Margarida Jorge, Rita Adão, Rita Duarte, Aida Duarte, Noélia Lopes, Maria Manuel Teixeira, Generosa Evid Based Complement Alternat Med Research Article The antioxidant and antimycotic activities of the essential oils and extracts of two native Portuguese Lavandula species, L. stoechas subsp. luisieri and L. pedunculata, were evaluated by in vitro assays. The total phenolics and flavonoids content were also determined. The antioxidant potential was assessed through DPPH radical scavenging, inhibition of lipid peroxidation (ILP), and DNA protection assays. All samples displayed a high DPPH scavenging activity, some of them showing concentration dependence. The majority of the samples were also able to inhibit lipid peroxidation. A strong correlation was observed between the results of DPPH and ILP assays and the flavonoids content of the samples. In the DNA protection assay, all the extracts were able to preserve DNA integrity. The antimycotic activity was performed against twelve fungi belonging to Basidiomycota and Ascomycota Divisions. L. stoechas subsp. luisieri exhibited the broadest activity spectra. L. pedunculata extracts were active against five fungi. Cryptococcus neoformans was the most sensitive, being inhibited by all the extracts. Our results led to the conclusion that L. stoechas subsp. luisieri and L. pedunculata can be useful as new sources of natural antioxidants and antimycotic agents, providing a possible valorization of the existing biodiversity and resources of Portuguese flora. Hindawi Publishing Corporation 2015 2015-04-01 /pmc/articles/PMC4397469/ /pubmed/25922611 http://dx.doi.org/10.1155/2015/570521 Text en Copyright © 2015 Rafael Baptista et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Baptista, Rafael Madureira, Ana Margarida Jorge, Rita Adão, Rita Duarte, Aida Duarte, Noélia Lopes, Maria Manuel Teixeira, Generosa Antioxidant and Antimycotic Activities of Two Native Lavandula Species from Portugal |
title | Antioxidant and Antimycotic Activities of Two Native Lavandula Species from Portugal |
title_full | Antioxidant and Antimycotic Activities of Two Native Lavandula Species from Portugal |
title_fullStr | Antioxidant and Antimycotic Activities of Two Native Lavandula Species from Portugal |
title_full_unstemmed | Antioxidant and Antimycotic Activities of Two Native Lavandula Species from Portugal |
title_short | Antioxidant and Antimycotic Activities of Two Native Lavandula Species from Portugal |
title_sort | antioxidant and antimycotic activities of two native lavandula species from portugal |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397469/ https://www.ncbi.nlm.nih.gov/pubmed/25922611 http://dx.doi.org/10.1155/2015/570521 |
work_keys_str_mv | AT baptistarafael antioxidantandantimycoticactivitiesoftwonativelavandulaspeciesfromportugal AT madureiraanamargarida antioxidantandantimycoticactivitiesoftwonativelavandulaspeciesfromportugal AT jorgerita antioxidantandantimycoticactivitiesoftwonativelavandulaspeciesfromportugal AT adaorita antioxidantandantimycoticactivitiesoftwonativelavandulaspeciesfromportugal AT duarteaida antioxidantandantimycoticactivitiesoftwonativelavandulaspeciesfromportugal AT duartenoelia antioxidantandantimycoticactivitiesoftwonativelavandulaspeciesfromportugal AT lopesmariamanuel antioxidantandantimycoticactivitiesoftwonativelavandulaspeciesfromportugal AT teixeiragenerosa antioxidantandantimycoticactivitiesoftwonativelavandulaspeciesfromportugal |