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Advances in the development of SUMO specific protease (SENP) inhibitors

Sumoylation is a reversible post-translational modification that involves the covalent attachment of small ubiquitin-like modifier (SUMO) proteins to their substrate proteins. Prior to their conjugation, SUMO proteins need to be proteolytically processed from its precursor form to mature or active f...

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Detalles Bibliográficos
Autores principales: Kumar, Ashutosh, Zhang, Kam Y.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397505/
https://www.ncbi.nlm.nih.gov/pubmed/25893082
http://dx.doi.org/10.1016/j.csbj.2015.03.001