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Involvement of a C-terminal motif in the interference of primate lentiviral Vpu proteins with CD1d-mediated antigen presentation

The HIV-1 accessory protein Vpu is emerging as a critical factor for viral evasion from innate immunity. We have previously shown that the Vpu proteins of two HIV-1 group M subtype B strains (NL4-3 and BaL) down-regulate CD1d from the surface of infected dendritic cells (DCs) and inhibit their cross...

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Detalles Bibliográficos
Autores principales: Bächle, Susanna M., Sauter, Daniel, Sibitz, Sabrina, Sandberg, Johan K., Kirchhoff, Frank, Moll, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397644/
https://www.ncbi.nlm.nih.gov/pubmed/25872908
http://dx.doi.org/10.1038/srep09675