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Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells

Spinal motor neurons (MNs) control diverse motor tasks including respiration, posture and locomotion that are disrupted by neurodegenerative diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy. Methods directing MN differentiation from stem cells have been developed to enable...

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Detalles Bibliográficos
Autores principales: Adams, Katrina L., Rousso, David L., Umbach, Joy A., Novitch, Bennett G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397664/
https://www.ncbi.nlm.nih.gov/pubmed/25868900
http://dx.doi.org/10.1038/ncomms7778