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Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells
Spinal motor neurons (MNs) control diverse motor tasks including respiration, posture and locomotion that are disrupted by neurodegenerative diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy. Methods directing MN differentiation from stem cells have been developed to enable...
Autores principales: | Adams, Katrina L., Rousso, David L., Umbach, Joy A., Novitch, Bennett G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397664/ https://www.ncbi.nlm.nih.gov/pubmed/25868900 http://dx.doi.org/10.1038/ncomms7778 |
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