A possible role for AMP-activated protein kinase activated by metformin and AICAR in human granulosa cells

BACKGROUND: Women with polycystic ovary syndrome (PCOS) are generally insulin- resistant and are consequently often treated with metformin. We investigated the effect of metformin and AICAR on the AMP-activated protein kinase (AMPK) pathway. METHODS: We evaluated the effects of 5-amino-imidazole-4-c...

Descripción completa

Detalles Bibliográficos
Autores principales: Kai, Yufuko, Kawano, Yasushi, Yamamoto, Hanae, Narahara, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397678/
https://www.ncbi.nlm.nih.gov/pubmed/25889494
http://dx.doi.org/10.1186/s12958-015-0023-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397678/
https://www.ncbi.nlm.nih.gov/pubmed/25889494
http://dx.doi.org/10.1186/s12958-015-0023-2

Ejemplares similares