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Protective efficacy of recombinant canine adenovirus type-2 expressing TgROP18 (CAV-2-ROP18) against acute and chronic Toxoplasma gondii infection in mice

BACKGROUND: The use of recombinant viral vectors expressing T. gondii antigens is a safe and efficient approach to induce immune responses against the parasite, as well as a valuable tool for vaccine development. We have previously prolonged the survival time of mice challenged with the RH strain of...

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Detalles Bibliográficos
Autores principales: Li, Xiu-Zhen, Wang, Xiao-Hu, Xia, Li-Jun, Weng, Ya-Biao, Hernandez, Jorge A, Tu, Li-Qing, Li, Lu-Tao, Li, Shou-Jun, Yuan, Zi-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397727/
https://www.ncbi.nlm.nih.gov/pubmed/25886737
http://dx.doi.org/10.1186/s12879-015-0815-1