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Protective efficacy of recombinant canine adenovirus type-2 expressing TgROP18 (CAV-2-ROP18) against acute and chronic Toxoplasma gondii infection in mice
BACKGROUND: The use of recombinant viral vectors expressing T. gondii antigens is a safe and efficient approach to induce immune responses against the parasite, as well as a valuable tool for vaccine development. We have previously prolonged the survival time of mice challenged with the RH strain of...
Autores principales: | Li, Xiu-Zhen, Wang, Xiao-Hu, Xia, Li-Jun, Weng, Ya-Biao, Hernandez, Jorge A, Tu, Li-Qing, Li, Lu-Tao, Li, Shou-Jun, Yuan, Zi-Guo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397727/ https://www.ncbi.nlm.nih.gov/pubmed/25886737 http://dx.doi.org/10.1186/s12879-015-0815-1 |
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