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Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma

BACKGROUND: Determining the cellular and molecular phenotypes of inflammation in asthma can identify patient populations that may best benefit from targeted therapies. Although elevated IL-6 and polymorphisms in IL-6 signalling are associated with lung dysfunction in asthma, it remains unknown if el...

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Detalles Bibliográficos
Autores principales: Chu, Derek K, Al-Garawi, Amal, Llop-Guevara, Alba, Pillai, Regina A, Radford, Katherine, Shen, Pamela, Walker, Tina D, Goncharova, Susanna, Calhoun, William J, Nair, Parameswaran, Jordana, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397814/
https://www.ncbi.nlm.nih.gov/pubmed/25878673
http://dx.doi.org/10.1186/s13223-015-0081-1