Cytochrome P450 2B6 genetic variants are associated with plasma nevirapine levels and clinical response in HIV-1 infected Kenyan women: a prospective cohort study

BACKGROUND: Polymorphisms in cytochrome P450 2B6 (CYP2B6) affect the steady state plasma concentration of nevirapine. CYP2B6 516G>T and 983T>C are common in African populations, but data on their influence on plasma nevirapine concentration and clinical response in African women are limited. W...

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Detalles Bibliográficos
Autores principales: Oluka, Margaret Ngwono, Okalebo, Faith Apolot, Guantai, Anastasia Nkatha, McClelland, R Scott, Graham, Susan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397818/
https://www.ncbi.nlm.nih.gov/pubmed/25878720
http://dx.doi.org/10.1186/s12981-015-0052-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397818/
https://www.ncbi.nlm.nih.gov/pubmed/25878720
http://dx.doi.org/10.1186/s12981-015-0052-0

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