Increased soluble phagocytic receptors sMer, sTyro3 and sAxl and reduced phagocytosis in Juvenile-onset Systemic Lupus Erythematosus

BACKGROUND: The TAM-receptor tyrosine kinase family, Tyro3, Axl and Mer are key to apoptotic cell clearance. Reduced phagocytic clearance in systemic lupus erythematosus (SLE) leads to prolonged exposure of nuclear autoantigen to the immune system. Here we measure the levels of TAM receptors and the...

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Detalles Bibliográficos
Autores principales: Ballantine, Lucy, Midgley, Angela, Harris, David, Richards, Ella, Burgess, Sarah, Beresford, Michael W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397859/
https://www.ncbi.nlm.nih.gov/pubmed/25878564
http://dx.doi.org/10.1186/s12969-015-0007-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397859/
https://www.ncbi.nlm.nih.gov/pubmed/25878564
http://dx.doi.org/10.1186/s12969-015-0007-y

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