Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli

BACKGROUND: Lipopolysaccharide (LPS) and interferon-γ (IFNγ) increase expression of tumour necrosis factor-α (TNFα) that characterizes the M1 activation state of macrophages. Whereas it is accepted that the immune system undergoes changes with age, there is inconsistency in the literature with respe...

Descripción completa

Detalles Bibliográficos
Autores principales: Barrett, James P, Costello, Derek A, O’Sullivan, Joan, Cowley, Thelma R, Lynch, Marina A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397943/
https://www.ncbi.nlm.nih.gov/pubmed/25890218
http://dx.doi.org/10.1186/s12974-015-0287-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397943/
https://www.ncbi.nlm.nih.gov/pubmed/25890218
http://dx.doi.org/10.1186/s12974-015-0287-7

Ejemplares similares