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Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli

BACKGROUND: Lipopolysaccharide (LPS) and interferon-γ (IFNγ) increase expression of tumour necrosis factor-α (TNFα) that characterizes the M1 activation state of macrophages. Whereas it is accepted that the immune system undergoes changes with age, there is inconsistency in the literature with respe...

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Detalles Bibliográficos
Autores principales:	Barrett, James P, Costello, Derek A, O’Sullivan, Joan, Cowley, Thelma R, Lynch, Marina A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397943/ https://www.ncbi.nlm.nih.gov/pubmed/25890218 http://dx.doi.org/10.1186/s12974-015-0287-7

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