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Blockade of Autophagy Aggravates Endoplasmic Reticulum Stress and Improves Paclitaxel Cytotoxicity in Human Cervical Cancer Cells

PURPOSE: Autophagy is one of the ways to degrade unfolded proteins after endoplasmic reticulum (ER) stress. The purpose of this study is to determine whether a blockade of autophagy leads to aggravated endoplasmic reticulum stress, which then induces cells apoptosis in HeLa cells treated with paclit...

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Detalles Bibliográficos
Autores principales: Xu, Li, Liu, Jing-Hua, Zhang, Jing, Zhang, Na, Wang, Zan-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398113/
https://www.ncbi.nlm.nih.gov/pubmed/25578058
http://dx.doi.org/10.4143/crt.2013.222