Epoxide based inhibitors of the hepatitis C virus non-structural 2 autoprotease

Hepatitis C virus (HCV) non-structural 2 (NS2) encodes an essential protease activity responsible for processing at the NS2–NS3 junction which represents an attractive antiviral target. Attempts to inhibit the NS2 autoprotease with mechanism-based protease inhibitors and substrate peptides have had...

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Detalles Bibliográficos
Autores principales: Shaw, Joseph, Fishwick, Colin W.G., Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398321/
https://www.ncbi.nlm.nih.gov/pubmed/25703928
http://dx.doi.org/10.1016/j.antiviral.2015.02.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398321/
https://www.ncbi.nlm.nih.gov/pubmed/25703928
http://dx.doi.org/10.1016/j.antiviral.2015.02.005

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