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Epoxide based inhibitors of the hepatitis C virus non-structural 2 autoprotease

Hepatitis C virus (HCV) non-structural 2 (NS2) encodes an essential protease activity responsible for processing at the NS2–NS3 junction which represents an attractive antiviral target. Attempts to inhibit the NS2 autoprotease with mechanism-based protease inhibitors and substrate peptides have had...

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Detalles Bibliográficos
Autores principales:	Shaw, Joseph, Fishwick, Colin W.G., Harris, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398321/ https://www.ncbi.nlm.nih.gov/pubmed/25703928 http://dx.doi.org/10.1016/j.antiviral.2015.02.005

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