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Overexpression of the Novel Senescence Marker β-Galactosidase (GLB1) in Prostate Cancer Predicts Reduced PSA Recurrence

PURPOSE: Senescence is a terminal growth arrest that functions as a tumor suppressor in aging and precancerous cells and is a response to selected anticancer compounds. Lysosomal-β-galactosidase (GLB1) hydrolyzes β-galactose from glycoconjugates and is the origin of senescence-associated β-gal activ...

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Detalles Bibliográficos
Autores principales: Wagner, Jennifer, Damaschke, Nathan, Yang, Bing, Truong, Matthew, Guenther, Chad, McCormick, Johnathon, Huang, Wei, Jarrard, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398352/
https://www.ncbi.nlm.nih.gov/pubmed/25876105
http://dx.doi.org/10.1371/journal.pone.0124366