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Chrysin Inhibits Tumor Promoter-Induced MMP-9 Expression by Blocking AP-1 via Suppression of ERK and JNK Pathways in Gastric Cancer Cells

Cell invasion is a crucial mechanism of cancer metastasis and malignancy. Matrix metalloproteinase-9 (MMP-9) is an important proteolytic enzyme involved in the cancer cell invasion process. High expression levels of MMP-9 in gastric cancer positively correlate with tumor aggressiveness and have a si...

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Detalles Bibliográficos
Autores principales: Xia, Yong, Lian, Sen, Khoi, Pham Ngoc, Yoon, Hyun Joong, Joo, Young Eun, Chay, Kee Oh, Kim, Kyung Keun, Do Jung, Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398353/
https://www.ncbi.nlm.nih.gov/pubmed/25875631
http://dx.doi.org/10.1371/journal.pone.0124007