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The Role of Lipoprotein-Associated Phospholipase A₂ in a Murine Model of Experimental Autoimmune Uveoretinitis

Macrophage activation is, in part, regulated via hydrolysis of oxidised low density lipoproteins by Lipoprotein-Associated phospholipase A(2) (Lp-PLA(2)), resulting in increased macrophage migration, pro-inflammatory cytokine release and chemokine expression. In uveitis, tissue damage is mediated as...

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Detalles Bibliográficos
Autores principales: Crawford, G. L., Boldison, J., Copland, D. A., Adamson, P., Gale, D., Brandt, M., Nicholson, L. B., Dick, A. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398387/
https://www.ncbi.nlm.nih.gov/pubmed/25874928
http://dx.doi.org/10.1371/journal.pone.0122093