Cargando…

The Role of Lipoprotein-Associated Phospholipase A₂ in a Murine Model of Experimental Autoimmune Uveoretinitis

Macrophage activation is, in part, regulated via hydrolysis of oxidised low density lipoproteins by Lipoprotein-Associated phospholipase A(2) (Lp-PLA(2)), resulting in increased macrophage migration, pro-inflammatory cytokine release and chemokine expression. In uveitis, tissue damage is mediated as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Crawford, G. L., Boldison, J., Copland, D. A., Adamson, P., Gale, D., Brandt, M., Nicholson, L. B., Dick, A. D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398387/ https://www.ncbi.nlm.nih.gov/pubmed/25874928 http://dx.doi.org/10.1371/journal.pone.0122093

Ejemplares similares

Tissue-Resident Exhausted Effector Memory CD8(+) T Cells Accumulate in the Retina during Chronic Experimental Autoimmune Uveoretinitis
por: Boldison, Joanne, et al.
Publicado: (2014)

Assessment and In Vivo Scoring of Murine Experimental Autoimmune Uveoretinitis Using Optical Coherence Tomography
por: Chu, Colin J., et al.
Publicado: (2013)

The Microbiota Determines Susceptibility to Experimental Autoimmune Uveoretinitis
por: Heissigerova, Jarmila, et al.
Publicado: (2016)

Treatment of experimental autoimmune uveoretinitis with different natural compounds
por: LI, MAN, et al.
Publicado: (2016)

Expression Analysis of Cytokine and Chemokine Genes during the Natural Course of Murine Experimental Autoimmune Uveoretinitis
por: Hashida, Noriyasu, et al.
Publicado: (2012)

Maturation-Resistant Dendritic Cells Ameliorate Experimental Autoimmune Uveoretinitis
por: Oh, Keunhee, et al.
Publicado: (2011)

Effects of Heme Oxygenase-1 Inducer and Inhibitor on Experimental Autoimmune Uveoretinitis
por: Jang, Jeong Un, et al.
Publicado: (2007)

Osteopontin is a biomarker for early autoimmune uveoretinitis
por: Kim, Jeongtae, et al.
Publicado: (2021)

Experimental autoimmune uveoretinitis (EAU) versus experimental allergic encephalomyelitis (EAE): a comparison of T cell-mediated mechanisms.
por: Calder, V L, et al.
Publicado: (1992)

IFN-β Inhibits the Increased Expression of IL-9 during Experimental Autoimmune Uveoretinitis
por: Yang, Yan, et al.
Publicado: (2012)

Treatment of experimental autoimmune uveoretinitis with peroxisome proliferator-activated receptor α agonist fenofibrate
por: Osada, Miho, et al.
Publicado: (2014)

Lipopolysaccharide‐primed heterotolerant dendritic cells suppress experimental autoimmune uveoretinitis by multiple mechanisms
por: Klaska, Izabela P., et al.
Publicado: (2016)

Regulatory Effects of IFN-β on the Development of Experimental Autoimmune Uveoretinitis in B10RIII Mice
por: Sun, Min, et al.
Publicado: (2011)

Therapeutic effect of the potent IL-12/IL-23 inhibitor STA-5326 on experimental autoimmune uveoretinitis
por: Keino, Hiroshi, et al.
Publicado: (2008)

Correction: Regulatory Effects of IFN-β on the Development of Experimental Autoimmune Uveoretinitis in B10RIII Mice
por: Sun, Min, et al.
Publicado: (2011)

Abrogation of Rbpj Attenuates Experimental Autoimmune Uveoretinitis by Inhibiting IL-22-Producing CD4(+) T Cells
por: Bhuyan, Zaied Ahmed, et al.
Publicado: (2014)

Chitosan Oligosaccharides Suppress Nuclear Factor-Kappa B Activation and Ameliorate Experimental Autoimmune Uveoretinitis in Mice
por: Hsu, Sheng-Min, et al.
Publicado: (2020)

MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis
por: Shigemoto-Kuroda, Taeko, et al.
Publicado: (2017)

AAV2-Mediated Subretinal Gene Transfer of hIFN-α Attenuates Experimental Autoimmune Uveoretinitis in Mice
por: Tian, Lichun, et al.
Publicado: (2011)

Depletion of Retinal Dopaminergic Activity in a Mouse Model of Rod Dysfunction Exacerbates Experimental Autoimmune Uveoretinitis: A Role for the Gateway Reflex
por: Stofkova, Andrea, et al.
Publicado: (2021)

AAV2-Mediated Combined Subretinal Delivery of IFN-α and IL-4 Reduces the Severity of Experimental Autoimmune Uveoretinitis
por: Tian, Lichun, et al.
Publicado: (2012)

AAV2-Mediated Subretinal Gene Transfer of mIL-27p28 Attenuates Experimental Autoimmune Uveoretinitis in Mice
por: Shao, Ju, et al.
Publicado: (2012)

Parabiosis reveals the correlation between the recruitment of circulating antigen presenting cells to the retina and the induction of spontaneous autoimmune uveoretinitis
por: McPherson, Scott W., et al.
Publicado: (2022)

In vivo multi-modal imaging of experimental autoimmune uveoretinitis in transgenic reporter mice reveals the dynamic nature of inflammatory changes during disease progression
por: Chen, Xiangting, et al.
Publicado: (2015)

Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100 beta molecule, a calcium binding protein of astroglia
Publicado: (1994)

Photopic light-mediated down-regulation of local α(1A)-adrenergic signaling protects blood-retina barrier in experimental autoimmune uveoretinitis
por: Stofkova, Andrea, et al.
Publicado: (2019)

Re-programming immunosurveillance in persistent non-infectious ocular inflammation
por: Epps, Simon J., et al.
Publicado: (2018)

Longitudinal Intravital Imaging of the Retina Reveals Long-term Dynamics of Immune Infiltration and Its Effects on the Glial Network in Experimental Autoimmune Uveoretinitis, without Evident Signs of Neuronal Dysfunction in the Ganglion Cell Layer
por: Bremer, Daniel, et al.
Publicado: (2016)

Cytosolic phospholipase A(2)α–deficient mice are resistant to experimental autoimmune encephalomyelitis
por: Marusic, Suzana, et al.
Publicado: (2005)

B cell depletion reduces T cell activation in pancreatic islets in a murine autoimmune diabetes model
por: Da Rosa, Larissa C., et al.
Publicado: (2018)

Secreted phospholipase A2 activity in experimental autoimmune encephalomyelitis and multiple sclerosis
por: Cunningham, Timothy J, et al.
Publicado: (2006)

Oxidized phospholipids and lipoprotein-associated phospholipase A(2) as important determinants of Lp(a) functionality and pathophysiological role
por: Tselepis, Alexandros D.
Publicado: (2018)

Lipoprotein associated phospholipase A(2): role in atherosclerosis and utility as a biomarker for cardiovascular risk
por: Colley, Kenneth J., et al.
Publicado: (2011)

Lipoprotein-associated phospholipase A(2): A paradigm for allosteric regulation by membranes
por: Mouchlis, Varnavas D., et al.
Publicado: (2022)

Lipoprotein‐associated phospholipase A2: The story continues
por: Huang, Fubao, et al.
Publicado: (2019)

Quantitative Assessment of Experimental Ocular Inflammatory Disease
por: Bradley, Lydia J., et al.
Publicado: (2021)

Long-term efficacy and safety of infliximab and cyclosporine combination therapy for refractory uveoretinitis in Behçet’s disease
por: Katsuyama, Atsuko, et al.
Publicado: (2019)

The role of lipoprotein-associated phospholipase A2 in acute kidney injury of septic mice
por: Liang, Guiwen, et al.
Publicado: (2020)

Lipoprotein-associated phospholipase A2, homocysteine, and Alzheimer's disease
por: Doody, Rachelle S., et al.
Publicado: (2015)

Racial variation in lipoprotein-associated phospholipase A(2 )in older adults
por: Lee, Keane K, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_q5eboriq3p3hrr1s86n9p1jfk4