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Genome-Wide Analysis of In Vivo Binding of the Master Regulator DasR in Streptomyces coelicolor Identifies Novel Non-Canonical Targets

Streptomycetes produce a wealth of natural products, including over half of all known antibiotics. It was previously demonstrated that N-acetylglucosamine and secondary metabolism are closely entwined in streptomycetes. Here we show that DNA recognition by the N-acetylglucosamine-responsive regulato...

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Detalles Bibliográficos
Autores principales: Świątek-Połatyńska, Magdalena A., Bucca, Giselda, Laing, Emma, Gubbens, Jacob, Titgemeyer, Fritz, Smith, Colin P., Rigali, Sébastien, van Wezel, Gilles P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398421/
https://www.ncbi.nlm.nih.gov/pubmed/25875084
http://dx.doi.org/10.1371/journal.pone.0122479