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Genome-Wide Analysis of In Vivo Binding of the Master Regulator DasR in Streptomyces coelicolor Identifies Novel Non-Canonical Targets
Streptomycetes produce a wealth of natural products, including over half of all known antibiotics. It was previously demonstrated that N-acetylglucosamine and secondary metabolism are closely entwined in streptomycetes. Here we show that DNA recognition by the N-acetylglucosamine-responsive regulato...
Autores principales: | Świątek-Połatyńska, Magdalena A., Bucca, Giselda, Laing, Emma, Gubbens, Jacob, Titgemeyer, Fritz, Smith, Colin P., Rigali, Sébastien, van Wezel, Gilles P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398421/ https://www.ncbi.nlm.nih.gov/pubmed/25875084 http://dx.doi.org/10.1371/journal.pone.0122479 |
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