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Formalin Evokes Calcium Transients from the Endoplasmatic Reticulum

The formalin test is the most widely used behavioral screening test for analgesic compounds. The cellular mechanism of action of formaldehyde, inducing a typically biphasic pain-related behavior in rodents is addressed in this study. The chemoreceptor channel TRPA1 was suggested as primary transduce...

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Detalles Bibliográficos
Autores principales: Fischer, Michael J. M., Soller, Kailey J., Sauer, Susanne K., Kalucka, Joanna, Veglia, Gianluigi, Reeh, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398422/
https://www.ncbi.nlm.nih.gov/pubmed/25875358
http://dx.doi.org/10.1371/journal.pone.0123762