Cargando…

Atorvastatin Calcium Inhibits Phenotypic Modulation of PDGF-BB-Induced VSMCs via Down-Regulation the Akt Signaling Pathway

Plasticity of vascular smooth muscle cells (VSMCs) plays a central role in the onset and progression of proliferative vascular diseases. In adult tissue, VSMCs exist in a physiological contractile-quiescent phenotype, which is defined by lack of the ability of proliferation and migration, while high...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Shuang, Liu, Baoqin, Kong, Dehui, Li, Si, Li, Chao, Wang, Huaqin, Sun, Yingxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398430/
https://www.ncbi.nlm.nih.gov/pubmed/25874930
http://dx.doi.org/10.1371/journal.pone.0122577