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Overexpression of Cytoplasmic TcSIR2RP1 and Mitochondrial TcSIR2RP3 Impacts on Trypanosoma cruzi Growth and Cell Invasion

BACKGROUND: Trypanosoma cruzi is a protozoan pathogen responsible for Chagas disease. Current therapies are inadequate because of their severe host toxicity and numerous side effects. The identification of new biotargets is essential for the development of more efficient therapeutic alternatives. In...

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Detalles Bibliográficos
Autores principales: Ritagliati, Carla, Alonso, Victoria L., Manarin, Romina, Cribb, Pamela, Serra, Esteban C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398437/
https://www.ncbi.nlm.nih.gov/pubmed/25875650
http://dx.doi.org/10.1371/journal.pntd.0003725