Cargando…
Overexpression of Cytoplasmic TcSIR2RP1 and Mitochondrial TcSIR2RP3 Impacts on Trypanosoma cruzi Growth and Cell Invasion
BACKGROUND: Trypanosoma cruzi is a protozoan pathogen responsible for Chagas disease. Current therapies are inadequate because of their severe host toxicity and numerous side effects. The identification of new biotargets is essential for the development of more efficient therapeutic alternatives. In...
Autores principales: | Ritagliati, Carla, Alonso, Victoria L., Manarin, Romina, Cribb, Pamela, Serra, Esteban C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398437/ https://www.ncbi.nlm.nih.gov/pubmed/25875650 http://dx.doi.org/10.1371/journal.pntd.0003725 |
Ejemplares similares
-
Mitochondrial Sirtuin TcSir2rp3 Affects TcSODA Activity and Oxidative Stress Response in Trypanosoma cruzi
por: dos Santos Moura, Leila, et al.
Publicado: (2021) -
Trypanosoma cruzi High Mobility Group B (TcHMGB) can act as an inflammatory mediator on mammalian cells
por: Cribb, Pamela, et al.
Publicado: (2017) -
Construction of three new Gateway(®) expression plasmids for
Trypanosoma cruzi
por: Alonso, Victoria L, et al.
Publicado: (2014) -
The mitochondrial SIR2 related protein 2 (SIR2RP2) impacts Leishmania donovani growth and infectivity
por: Mittal, Nimisha, et al.
Publicado: (2017) -
Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity
por: Tavernelli, Luis Emilio, et al.
Publicado: (2019)