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Role of the EHD2 Unstructured Loop in Dimerization, Protein Binding and Subcellular Localization
The C-terminal Eps 15 Homology Domain proteins (EHD1-4) play important roles in regulating endocytic trafficking. EHD2 is the only family member whose crystal structure has been solved, and it contains an unstructured loop consisting of two proline-phenylalanine (PF) motifs: KPFRKLNPF. In contrast,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398442/ https://www.ncbi.nlm.nih.gov/pubmed/25875965 http://dx.doi.org/10.1371/journal.pone.0123710 |