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Metabolic and Kidney Disorders Correlate with High Atazanavir Concentrations in HIV-Infected Patients: Is It Time to Revise Atazanavir Dosages?

INTRODUCTION: Ritonavir-boosted atazanavir (ATV/r) is a relatively well tolerated antiretroviral drug. However, side effects including hyperbilirubinemia, dyslipidemia, nephrolithiasis and cholelithiasis have been reported in the medium and long term. Unboosted ATV may be selected for some patients...

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Detalles Bibliográficos
Autores principales: Gervasoni, Cristina, Meraviglia, Paola, Minisci, Davide, Ferraris, Laurenzia, Riva, Agostino, Landonio, Simona, Cozzi, Valeria, Charbe, Nitin, Molinari, Lara, Rizzardini, Giuliano, Clementi, Emilio, Galli, Massimo, Cattaneo, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398451/
https://www.ncbi.nlm.nih.gov/pubmed/25875091
http://dx.doi.org/10.1371/journal.pone.0123670