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Evidence for a Novel Mechanism of Antimicrobial Action of a Cyclic R-,W-Rich Hexapeptide

The development of antimicrobial peptides as new class of antibiotic agents requires structural characterisation and understanding of their diverse mechanisms of action. As the cyclic hexapeptide cWFW (cyclo(RRRWFW)) does not exert its rapid cell killing activity by membrane permeabilisation, in thi...

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Detalles Bibliográficos
Autores principales: Scheinpflug, Kathi, Krylova, Oxana, Nikolenko, Heike, Thurm, Charley, Dathe, Margitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398456/
https://www.ncbi.nlm.nih.gov/pubmed/25875357
http://dx.doi.org/10.1371/journal.pone.0125056