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Evolution of the Perlecan/HSPG2 Gene and Its Activation in Regenerating Nematostella vectensis
The heparan sulfate proteoglycan 2 (HSPG2)/perlecan gene is ancient and conserved in all triploblastic species. Its presence maintains critical cell boundaries in tissue and its large (up to ~900 kDa) modular structure has prompted speculation about the evolutionary origin of the gene. The gene’s co...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398486/ https://www.ncbi.nlm.nih.gov/pubmed/25876075 http://dx.doi.org/10.1371/journal.pone.0124578 |